July 11, 2025

Cancer Gene Therapy Market $26.8 Bn by 2034 Growth

The global cancer gene therapy market size was evaluated at around USD 4.55 billion in 2024 and it is projected to hit around USD 26.80 billion by 2034, growing at a CAGR of 19.40% from 2025 to 2034. Cancer Gene Therapy Market Size 2025 to 2034

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Cancer Gene Therapy Market Overview

Cancer gene therapy is an innovative approach that aims to treat or prevent cancer by modifying the genetic material within a patient’s cells. Unlike traditional therapies that may harm healthy cells, gene therapy offers the promise of targeted treatment with minimal side effects. The market is gaining traction as advancements in biotechnology, precision medicine, and genomic research create new possibilities for curing various cancers through genetic intervention.

Cancer Gene Therapy Market Growth

The cancer gene therapy market is undergoing remarkable expansion, fueled by rising global cancer incidence and an urgent need for more effective treatments. In 2024, the market reached approximately USD 4.55 billion, and projections estimate it will soar to USD 26.80 billion by 2034. This substantial growth, marked by a CAGR of 19.40% from 2025 to 2034, underscores increasing confidence in gene therapy as a mainstream treatment option.

Supportive regulatory frameworks, greater R&D investments, and successful clinical trials are also contributing to the market’s momentum. Gene-editing technologies like CRISPR, viral and non-viral vectors, and precision targeting mechanisms are becoming more refined, making gene therapies more accessible and efficient. Pharmaceutical companies and biotech firms are expanding their pipelines to include gene therapies as integral parts of their oncology portfolios.

Cancer Gene Therapy Market Dynamics

Driven 

  • Rising prevalence of cancer globally
  • Advances in gene editing technologies such as CRISPR-Cas9
  • Growing support from regulatory agencies for fast-track approvals

Opportunities

  • Expansion in emerging markets with increasing healthcare infrastructure
  • Development of combination therapies integrating gene therapy with immunotherapy
  • Potential of personalized gene therapies for rare and aggressive cancers

Challenges

  • High treatment costs and limited insurance coverage
  • Ethical concerns and regulatory complexities
  • Delivery challenges in targeting specific cells or tissues effectively

Applications in Cancer Gene Therapy Market 

Cancer gene therapy is primarily used in the treatment of various types of cancers such as lung cancer, breast cancer, pancreatic cancer, leukemia, lymphoma, and melanoma. It plays a critical role in delivering corrective genes, triggering cancer cell apoptosis, and enhancing the immune system’s ability to recognize and attack tumors.

Case Study Success of Oncolytic Viral Therapy

A notable example is the FDA-approved Talimogene laherparepvec (T-VEC), used in treating advanced melanoma. T-VEC uses a modified herpes simplex virus to target and destroy cancer cells without harming normal tissue. Its success demonstrates how gene therapy can effectively activate anti-tumor immune responses, paving the way for more viral-based therapies in clinical oncology.

Cancer Gene Therapy Market Trends

  • Increased Clinical Trials and FDA Approvals: Growing clinical success and more FDA approvals for gene-based oncology treatments are encouraging wider adoption and investment in gene therapy solutions.
  • Integration of AI and Genomics: Artificial intelligence is playing a significant role in analyzing genetic data, helping to personalize treatments and improve the precision of gene therapy approaches.
  • Shift Toward Non-viral Vectors: Non-viral delivery methods are gaining traction due to lower immunogenic risks and ease of production, expanding research in this segment.
  • Strategic Collaborations: Partnerships between biotech firms, research institutions, and pharmaceutical giants are accelerating innovation and commercialization of cancer gene therapies.

Read More:https://www.heathcareinsights.com/large-molecule-bioanalytical-market/

Top Companies in Cancer Gene Therapy Market

  • Novartis AG
  • Bristol Myers Squibb (Juno Therapeutics)
  • Bluebird Bio, Inc.
  • Adaptimmune Therapeutics plc
  • Intellia Therapeutics, Inc.
  • CRISPR Therapeutics AG
  • Ziopharm Oncology (Now Alaunos Therapeutics)
  • Poseida Therapeutics, Inc.
  • Sorrento Therapeutics, Inc.
  • GenSight Biologics
  • Orchard Therapeutics plc
  • Mustang Bio, Inc.
  • Cellectis S.A.
  • LogicBio Therapeutics, Inc.

Cancer Gene Therapy Market Segments

By Therapy Type

  • Gene transfer therapy
  • Oncolytic virotherapy
  • Gene-induced immunotherapy

By Vector Type

  • Viral vectors (Retroviruses, Lentiviruses, Adenoviruses)
  • Non-viral vectors (Liposomes, Nanoparticles, Plasmids)

By End User

  • Hospitals
  • Cancer Research Centers
  • Specialty Clinics
  • Biopharmaceutical Companies

Future Outlook

The future of the cancer gene therapy market is promising, with ongoing advancements poised to redefine cancer care. Personalized medicine, genome sequencing, and AI-driven diagnostics will further integrate gene therapy into clinical practice. As awareness and accessibility improve, gene therapy may soon become a standard treatment, offering hope to millions of patients worldwide and reshaping the future of cancer treatment.

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